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How enable google chrome browser to run local commands in Windows?

I am using a web development tool called Oracle APEX 21.1 to create an app which will run on the web for some users and as desktop app for other users. The application runs in a browser in both cases. My problem is with the users that will use it as a desktop app. Sometimes I need to run a local file or run a specific program from the computer the user uses to run the app. The user is instructed to use google chrome to use the app. My question is, is there a setting of google chrome that I can set to allow my app to access local files or run Windows commands? Is there any other way i.e an add-on? If not, is there any other browser that can do the job? P.S: In my app, I can make use of JavaScript, JQuery, Oracle PL/SQL. Of course, a browser simple setting to set is the best option for me, if any.

in browser you you have to do use "href" string like this :
window.location = "notes:///server/file";
"notes:///" program name
And "server/file" parameter for programe

Interacting with Web pages using selenium inside electron application

I want to create an electron application which contains a sidebar and a improvised Web browser next to the sidebar. When a user presses the button in the sidebar i need selenium to start Interacting with the webpage in the improvised browser.
I would like to know if its possible and if there are any tools that might help me.

Selenium is using browser's driver to make the connection between your code and the browser. I haven't heard about anything similar to your project, but you will need to make your own driver for your custom browser and define from where the browser is opened (since it will be located inside your application, not on local machine)

run windows application at client side from aspx.cs

I have windows application in c#.that is installed for client . I need run that window application from client side when user button click in asp.net web application
Explanation
I have task that scan hard copy from scanner . I developed web application in asp.net c#. I have search in Google to do this so many peoples are saying that is not possible due to permissions. so I developed windows application when I run that window application(c#) it scan the hard copy from scanner this window application run in background so I need to run this window application. when user button click in asp.net web application

You cannot run applications from a website on client's machine due to security & permissions.
However, your website probably can communicate with the scanner. Check this detailed answer.

While you cannot run the application from the browser, there is another option, if your application is already running in the background. Then you can make it listen to some local port and then ask the browser to redirect to the URL (consisting of localhost and that port, e.g. http://localhost:34554), so the application would receive an HTTP request and will know it needs to become active / show its window / etc. Using this technique, you could even pass some parameters to your application using query params in the URL.
Another option that allows you kinda run an application from the browser is Microsoft ClickOnce - it is just a simplified way of installing and running an application without the need for the user to download and manually run the installer.

Launching a desktop application from a browser(client web page)

I need to launch an application which is installed in the client machine when the user clicks the link in the client webpage from browser. for instance like launching the Goto meeting application from the client machine when clicking the URL link if installed else providing the download link.
I tried with ActiveXobject approach which works only with IE browser.And also check with FileAPI.
In the following link they mentioned about using Asynchronous Pluggable Protocol Handler. Since I'm new to it. Can you please guide me where to start.
Launch application from a browser
About the environment. My server application is in Asp.Net MVC platform.
Thanks in advance

Since the browser prohibits you from executing anything locally I think the best way to solve your problem would be to create Chrome/Firefox extensions.
Extensions are not bound and can be executed locally.

web app on mobiles with phonegap

I have a web application (chat room) in html + javascript that basically sends requests to the server every 5 seconds to check for new messages.
It already works on mobile but there are 2 main problems:
it does not beep (it works on pc) with new messages
when the browser is put on background, the javascript obviously stops being executed, therefore the connection to the server is lost and the client disconnected.
i was thinking of using phonegap not only to make it cross-platform but also to fix those problems stated above. would they be resolved with the use of phonegap?
thank you in advance.

phoneGap doesn't support custom push notification. it basically open a browser and expose you some native support via API.
in order to do some native actions like push notifications and/or sound playing i suggest you check out some of the plugins options available or even write your own for that.

Playing sounds can be done easily using the Media API. As for having the JavaScript run in the background it really depends on the OS. On Android the JS will continue to run if you leave the app via the home button but the back button kills the app so you would stop the JS. It is probably better to write a service that always runs in that case.
Alternatively you'd look at a push type solution to notify you of new messages.