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3 While Loops into a Single Loop?

I have to remove the commas, periods, and hyphens from an HTML text value. I do not want to write all 3 of these while loops, instead I only want one loop (any) to do all of this.
I already tried a while with multiple && and if else nested inside but i would always only just get the commas removed.
while(beg.indexOf(',') > -1)
{
beg = beg.replace(',','');
document.twocities.begins.value= beg;
}
while(beg.indexOf('-') > -1)
{
beg = beg.replace('-','');
document.twocities.begins.value= beg;
}
while(beg.indexOf('.') > -1)
{
beg= beg.replace('.','');
document.twocities.begins.value= beg;
}

You can do all this without loops by using regex.
Here is an example of removing all those characters using a single regex:
let str = "abc,d-e.fg,hij,1-2,34.56.7890"
str = str.replace(/[,.-]/g, "")
console.log(str)

No loops are necessary for this in the first place.
You can replace characters in a string with String.replace() and you can determine which characters and patterns to replace using regular expressions.
let sampleString = "This, is. a - test - - of, the, code. ";
console.log(sampleString.replace(/[,-.]/g, ""));

A single call to the replace function and using a regular expression suffice:
document.twocities.begins.value = beg = beg.replace(/[,.-]/g, "");
Regular expressions are a pattern matching language. The pattern employed here basically says "every occurrence of one of the characters ., ,, -)". Note that the slash / delimits the pattern while the suffix consists of flags controlling the matching process - in this case it is g (global) telling the engine to replace each occurrence ( as opposed to the first only without the flag ).
This site provides lots of info about regular expressions, their use in programming and implementations in different programming environments.
There are several online sites to test actual regular expression and what they match (including explanations), eg. Regex 101.
Even more details ... ;): You may use the .replace function with a string as the first argument (as you did in your code sample). However, only the first occurrence of the string searched for will be replaced - thus you would have to resort to loops. Specs of the .replace function (and of JS in general) can be found here.

Use regex like below.
let example = "This- is a,,., string.,";
console.log(example.replace(/[-.,]+/g, ""));

How to regex test a string for a pattern while excluding certain characters?

I'm getting nowhere with this...
I need to test a string if it contains %2 and at the same time does not contain /. I can't get it to work using regex. Here is what I have:
var re = new RegExp(/.([^\/]|(%2))*/g);
var s = "somePotentially%2encodedStringwhichMayContain/slashes";
console.log(re.test(s)) // true
Question:
How can I write a regex that checks a string if it contains %2 while not containing any / slashes?

While the link referred to by Sebastian S. is correct, there's an easier way to do this as you only need to check if a single character is not in the string.
/^[^\/]*%2[^\/]*$/
EDIT: Too late... Oh well :P

Try the following:
^(?!.*/).*%2

either use inverse matching as shown here: Regular expression to match a line that doesn't contain a word?
or use indexOf(char) in an if statement. indexOf returns the position of a string or char in a string. If not found, it will return -1:
var s = "test/";
if(s.indexOf("/")!=-1){
//contains "/"
}else {
//doesn't contain "/"
}

what's wrong with this regular expression? getting the hash part of an url

I´m trying to get the first part of a hash from a url (the part between the # and a /, a ? or the end of the string
So far now I came out with this:
r = /#(.*)[\?|\/|$]/
// OK
r.exec('http://localhost/item.html#hash/sub')
["#hash/", "hash"]
// OK
r.exec('http://localhost/item.html#hash?sub')
["#hash?", "hash"]
// WAT?
r.exec('http://localhost/item.html#hash')
null
I was expeting to receive "hash"
I tracked down the problem to
/#(.*)[$]/
r2.exec('http://localhost/item.html#hash')
null
any idea what could be wrong?

r = /#(.*)[\?|\/|$]/
When $ appears in [] (character class, it's the literal "$" character, not the end of input/line. In fact, your [\?|\/|$] part is equivalent to just [?/$|], which matches the 4 specific characters (including pipe).
Use this instead (JSFiddle)
r = /#(.+?)(\?|\/|$)/

You aren't supposed to write [$] (within a character class) unless you want to match the $ literally and not the end of line.
/#(.*)$/
Code:
var regex = /\#(.*)$/;
regex.exec('http://localhost/item.html#hash');
Output:
["#hash", "hash"]
Your regex: /#(.*)[\?|\/|$]/
//<problem>-----^ ^-----<problem>
| operator won't work within [], but within ()
$ will be treated literally within []
.* will match as much as possible. .*? will be non-greedy
On making the above changes,
you end up with /#(.*?)(\?|\/|$)/

I use http://regexpal.com/ to test my regular expressions.
Your problem here is that your regular expression wants a /. So it don't works with http://localhost/item.html#hash but it works with http://localhost/item.html#hash/
Try this one :
r = /#([^\?|\/|$]*)/

You can't use the $ end-of-string marker in a character class. You're probably better off just matching characaters that aren't / or ?, like this:
/#([^\?\/]*)/

Why Regex? Do it like this (nearly no regex):
var a = document.createElement('a');
a.href = 'http://localhost/item.html#hash/foo?bar';
console.log(a.hash.split(/[\/\?]/)[0]); // #hash
Just for the sake, if it is node.js you are working with:
var hash = require('url').parse('http://localhost/item.html#hash').hash;

I found this regular expression that seems to work
r = /#([^\/\?]*)/
r.exec('http://localhost/item.html#hash/sub')
["#hash", "hash"]
r.exec('http://localhost/item.html#hash?sub')
["#hash", "hash"]
r.exec('http://localhost/item.html#hash')
["#hash", "hash"]
Anyway, I still don't get why the original one isn't working

How do I make a regular expression that matches everything on a line after a given character?

If I have a String in JavaScript
key=value
How do I make a RegEx that matches key excluding =?
In other words:
var regex = //Regular Expression goes here
regex.exec("key=value")[0]//Should be "key"
How do I make a RegEx that matches value excluding =?
I am using this code to define a language for the Prism syntax highlighter so I do not control the JavaScript code doing the Regular Expression matching nor can I use split.

Well, you could do this:
/^[^=]*/ // anything not containing = at the start of a line
/[^=]*$/ // anything not containing = at the end of a line
It might be better to look into Prism's lookbehind property, and use something like this:
{
'pattern': /(=).*$/,
'lookbehind': true
}
According to the documentation this would cause the = character not to be part of the token this pattern matches.

use this regex (^.+?)=(.+?$)
group 1 contain key
group 2 contain value
but split is better solution

.*=(.*)
This will match anything after =
(.*)=.*
This will match anything before =
Look into greedy vs ungreedy quantifiers if you expect more than one = character.
Edit: as OP has clarified they're using javascript:
var str = "key=value";
var n=str.match(/(.*)=/i)[1]; // before =
var n=str.match(/=(.*)/i)[1]; // after =

var regex = /^[^=]*/;
regex.exec("key=value");

Split string in JavaScript using a regular expression

I'm trying to write a regex for use in javascript.
var script = "function onclick() {loadArea('areaog_og_group_og_consumedservice', '\x26roleOrd\x3d1');}";
var match = new RegExp("'[^']*(\\.[^']*)*'").exec(script);
I would like split to contain two elements:
match[0] == "'areaog_og_group_og_consumedservice'";
match[1] == "'\x26roleOrd\x3d1'";
This regex matches correctly when testing it at gskinner.com/RegExr/ but it does not work in my Javascript. This issue can be replicated by testing ir here http://www.regextester.com/.
I need the solution to work with Internet Explorer 6 and above.
Can any regex guru's help?

Judging by your regex, it looks like you're trying to match a single-quoted string that may contain escaped quotes. The correct form of that regex is:
'[^'\\]*(?:\\.[^'\\]*)*'
(If you don't need to allow for escaped quotes, /'[^']*'/ is all you need.) You also have to set the g flag if you want to get both strings. Here's the regex in its regex-literal form:
/'[^'\\]*(?:\\.[^'\\]*)*'/g
If you use the RegExp constructor instead of a regex literal, you have to double-escape the backslashes: once for the string literal and once for the regex. You also have to pass the flags (g, i, m) as a separate parameter:
var rgx = new RegExp("'[^'\\\\]*(?:\\\\.[^'\\\\]*)*'", "g");
while (result = rgx.exec(script))
print(result[0]);

The regex you're looking for is .*?('[^']*')\s*,\s*('[^']*'). The catch here is that, as usual, match[0] is the entire matched text (this is very normal) so it's not particularly useful to you. match[1] and match[2] are the two matches you're looking for.
var script = "function onclick() {loadArea('areaog_og_group_og_consumedservice', '\x26roleOrd\x3d1');}";
var parameters = /.*?('[^']*')\s*,\s*('[^']*')/.exec(script);
alert("you've done: loadArea("+parameters[1]+", "+parameters[2]+");");
The only issue I have with this is that it's somewhat inflexible. You might want to spend a little time to match function calls with 2 or 3 parameters?
EDIT
In response to you're request, here is the regex to match 1,2,3,...,n parameters. If you notice, I used a non-capturing group (the (?: ) part) to find many instances of the comma followed by the second parameter.
/.*?('[^']*')(?:\s*,\s*('[^']*'))*/

Maybe this:
'([^']*)'\s*,\s*'([^']*)'